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2015 ( Diabetes Care ), Lactobacillus reuteri supplementation improved incretin and insulin secretion in glucose-tolerant humans

These things can affect how well it absorbs or might leave a bruise

A doctor can increase it to 7 mg, then to 14 mg, depending on your blood sugar levels and weight

Tirzepatide achieves 20.9% at 72 weeks on 15mg, per SURMOUNT-1 (Jastreboff et al., NEJM 2022)