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Perinatal risk factors for childhood obesity and metabolic dysregulation
Gastric emptying was assessed 2 days pre-treatment and 24 h after the dose at day 2, day 30, and day 79
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27.2% lost at least 35%
Two unnatural amino acids (aminoisobutyric acid at positions 2 and 20, -methyl-leucine at position 13) confer protease resistance and allow the molecule to survive long enough in plasma for once-weekly dosing in clinical studies
Int J App Basic Med Res
