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Description
Participants were still losing weight at week 48, suggesting the true maximum potential remained unexplored

Tolessa T, Gutniak M, Holst JJ, Efendic S, Hellstrom PM

doi: 10.1111/dom.14979 [DOI] [PubMed] [Google Scholar] 15

Most improve with time and simple changes like adjusting meal size and staying hydrated

Exendin-4 induced retching-like behavior mediated by postsynaptic effect via AMPA receptors in the area postrema of mice

In addition, our approach is constrained by the limited number of genetic proxies available to GLP-1RAs, which would preclude further sensitivity analyses for horizontal pleiotropy [39]
