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Insulin remains the preferred choice only when GLP-1 drugs are contraindicated, unaffordable, or insufficient alone, or when the patient has Type 1 diabetes

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A substudy of the phase 2 clinical trial specifically examined body composition changes using dual-energy X-ray absorptiometry (DEXA), the gold standard for measuring lean and fat mass

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[14] [15] For those with specific athletic goals, sports nutrition consensus statements (including those from the International Olympic Committee and the British Dietetic Association's Sports Dietitians group) suggest protein intakes in the range of 1.62.2 g per kg of body weight per day to support muscle retention during periods of energy restriction