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Currently, there is no consensus among endocrinologists on the best diagnostic approach, management, or need for empiric glucocorticoid treatment during critical illness or before surgery

Doses are typically started low and gradually increased to help minimize side effects and allow the body to adjust

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in clinical trials it led to a weight loss of 15% to 20% of body weight after 16 months

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[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Wang V., Kuo T.-T., Huang E.Y.-K., Ma K.-H., Chou Y.-C., Fu Z.-Y., Lai L.-W., Jung J., Choi H.-I., Choi D.-S., et al