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J Clin Invest 117:21552163 Shu L, Matveyenko AV, Kerr-Conte J, Cho JH, McIntosh CH, Maedler K (2009) Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function

(2016) Novel extrapancreatic effects of incretin

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Updated April 13, 2023

P = 0.007 for superiority) in T2DM patients with a history of cardiovascular disease or current kidney disease in a recently completed trial (AMPLITUDE-O) [63]