new weight loss drug retatrutide for loss: Study shows 30% body weight Retatrutide Isn't a Weight Loss
Description
GLP-1 medications are not recommended for people with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2)

The index single-nucleotide polymorphism (SNP) of the main association was rs10305420 ( P = 2.9 10 10 , reference allele C, effect allele T), which conferred an additional 0.641% BMI loss per T allele, approximately equivalent to an additional 0.76 kg weight loss per allele (95% CI, [1.27, 0.34] kg)

Nicklas WJ, Youngster SK, Kindt MV, Heikkila RE
With respect to Musely, while the company claims its ingredients are FDA approved, its products are not, which it doesnt mention on product pages
The implications of this simple experiment are profound: cells in the small intestine can secrete factors (named hormones in 1905) that regulate pancreatic function and glucose metabolism

It is used to lower blood sugar in people with type 2 diabetes and is also used off-label for weight loss in people with obesity and overweight
