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In contrast, no benefits on the rate of decline in glomerular filtration rate have been seen in trials of DPP-4 inhibitors, perhaps because the renal actions of DPP-4 inhibitors are primarily mediated by potentiation of SDF-1, not GLP-1

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75% of US consumers say GLP-1s are a useful tool, not a magic cure - but 61% of users admit it can feel like cheating. The stigma is fading fast