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Secondary endpoints in the trial emulations as well as in their respective reference trials were not powered sufficiently to assess statistical agreement

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Patients' success stories reveal that tirzepatide not only facilitates significant weight reduction but also delivers improvements in metabolic health

Adults with overweight or obesity lost more weight with the GIP/GLP-1 dual agonist tirzepatide than the GLP-1 receptor agonist semaglutide, according to findings published in JAMA Internal Medicine

This can be tough when youre on a GLP-1, so have regular check-ins with your doctor and make sure youre on the right dose

Tirzepatide typically produces more weight loss than semaglutide at equivalent timepoints, which means a potentially larger caloric deficit and more pronounced initial fatigue