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Extracellular TDP-43 aggregates target MAPK/MAK/MRK overlapping kinase (MOK) and trigger caspase-3/IL-18 signaling in microglia
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Timeline Semaglutide: noticeable appetite and weight changes in weeks
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Tirzepatide, a dual GLP-1 and GIP receptor agonist, may help manage weight and metabolic dysfunction in polycystic ovary syndrome (PCOS) by targeting multiple pathways involved in appetite regulation and insulin signaling
