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While injectables dominate, the availability of oral formulations provides a convenient alternative for patients reluctant to use injections, improving treatment adherence

They are different molecules with different synthesis complexity and availability, so cross-compound price comparison is not meaningful

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73 Fewer studies have evaluated the risk of biliary disease, possibly due to impaired gallbladder emptying, 74 however, tirzepatide was shown to portend an increased risk (RR 1.97, 95% CI 1.143.42, I2 = 0.0%, p = 0.558)