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Real-World Trends vs Clinical Trial Protocols In clinical trials, dose escalation follows strict timelines
In animal experiments involving shrews (which are able to vomit), GLP-1RAs elicit frequent episodes of vomiting, while GIPRAs do not

285 , 723730 (2010) Castro, M., Nikolaev, V
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The GLP-1 receptor agonist liraglutide reverses mania-like alterations and memory deficits induced by D-amphetamine and augments lithium effects in mice: relevance for bipolar disorder