what is glp -1 Understanding semaglutide (GLP-1 RA): Are they the right choice for weight loss? GLP-1 Agonists: A Comprehensive Overview
Description
Permanent damage from GLP-1 therapy itself is extremely uncommon when used as directed by a licensed provider

Eat whatever you can tolerate that provides adequate protein

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These results translated to significant proportions of participants achieving clinically meaningful weight loss: 5% or More Weight Reduction: 92% (4 mg), 100% (8 mg), 100% (12 mg), and 27% (placebo) 10% or More Weight Reduction: 75% (4 mg), 91% (8 mg), 93% (12 mg), and 9% (placebo) 15% or More Weight Reduction: 60% (4 mg), 75% (8 mg), 83% (12 mg), and 2% (placebo) These data underscore retatrutides potential to deliver unprecedented weight loss in a significant portion of individuals with obesity

The 12mg group may have had different baseline compositions, or the additional weight loss at 12mg may have included a slightly higher proportion of lean tissue

Metformin Use Associated With Reduced Risk of Dementia in Patients With Diabetes: A Systematic Review and Meta-Analysis