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I n the future, innovation will likely focus on five key areas: long-acting formulations, oral delivery methods, multi-target approaches, combination therapies, and expanding the range of indications
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GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) have transformed diabetes and weight management, but emerging evidence links these medications to increased gallbladder complications
a value of less than 3.5 was considered diagnostic for insulin resistance [41]
In contrast, a randomized clinical trial did not observe any improvement in glycemic control and IR as well as in visceral fat area in diabetic hypogonadal men when T replacement therapy was administered for a short period [85,107,171]
