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Our data provide a rational template to facilitate the design of better GLP-2 analogues for therapeutic use and expand our knowledge on the biology of this receptor family

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It works by mimicking the action of the GLP-1 hormone, which naturally occurs in the body to regulate blood sugar levels and appetite

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In an attempt to assess CV efficacy of oral semaglutide after demonstrating its CV safety in the PIONEER-6 trial, a large CVOT ( N = 9,650) is currently ongoing (SOUL trial) to compare the risk of MACE composite outcome with oral semaglutide vs