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JACC Cardiovasc Imaging 2021;14(1):12830

A 2021 trial indicated that about 14% of users may not lose a clinically significant amount of weight even with the medication

PuszkarskaATaddeseBRevellJDaviesGFieldJHornigoldDet al

Consumer insights professionals should use this opportunity to prepare themselves not only for future GLP-1 growth but also for future health and weight loss trends

Insulin resistance/hyperinsulinemia: an important cardiovascular risk factor that has long been underestimated

Importantly, this study identified novel candidate genes linked to insulin secretion and T2D risk: ERO1B (ER stress and protein folding), HNRNPA2B1 (an RNA-binding protein regulating insulin levels), and RHOBTB3 (involved in secretory protein trafficking), whose inhibition reduced intracellular insulin (Grenko et al., 2024)