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[Google Scholar] 68.Kim JA, Lee S, Lee SH, Jung SY, Kim YH, Choi IY, et al

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N-terminally and C-terminally truncated forms of glucose-dependent insulinotropic polypeptide are high-affinity competitive antagonists of the human GIP receptor

6.8.1 Wnt/-catenin signaling In the case of Wnt/-catenin signaling (the canonical pathway), when the ligands (such as Wnt1, Wnt2, Wnt3, Wnt8a, and Wnt10b) bind to the Frizzled (FZD) receptors and LRP5/6 co-receptors, signaling is activated, leading to the recruitment of axis inhibition protein (AXIN1/2) and Dishevelled (DVL), which can inhibit the -catenin destruction complex (consisting of AXIN, GSK3, CK1, and APC) (233)

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