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Trial Registration The predefined protocol has been registered in PROSPERO having registration number of CRD42023473991

To Use: Select an area of skin
Calocurb is not indicated for patients with type 1 diabetes mellitus

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We evaluated the effects of metformin, administered at different intervals before an intraduodenal glucose infusion, on the subsequent glycaemic, insulinaemic and GLP-1 responses in metformin-treated type 2 diabetes
