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In the lungs, GLP-1RAs attenuate acute lung injury by maintaining alveolar-capillary barrier function, reducing neutrophil infiltration, and promoting surfactant protein expression, potentially through suppression of NLRP3 inflammasome activity

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While epigenetic mechanisms such as histone modifications and DNA methylation have undoubtedly provided valuable insights into the regulation of gene expression in NDDs, it is essential to recognize that these processes alone do not fully explain the complexities of NDD pathophysiology
