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Interestingly, in people with type 2 diabetes mellitus, who often exhibit glomerular hyperfiltration, GLP-1 receptor agonists stabilize or modestly reduce eGFR, an effect reminiscent of the initial declines observed with RAAS and SGLT2 inhibitors [64]

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However, the authors of this study noted that there were no clinically significant differences, and both drugs were effective for their intended uses

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Gerich JE, Meyer C, Woerle HJ, Stumvoll M