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The trials compared at least one obesity drug with lifestyle changes, a placebo, or another medication

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Lilly plans to submit orforglipron for type 2 diabetes to global agencies sometime in 2026

Repeatedly injecting in the same location can lead to lipohypertrophy, a condition characterized by lumpy, thickened areas of fatty tissue that can impair medication absorption and lead to unpredictable blood glucose levels

The most clinically relevant of these is delayed gastric emptying

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