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Why Weight Regain Occurs : Biological adaptations that promoted weight gain initially remain present Appetite and food preoccupation often return when medication stopped Metabolic rate may decrease during weight loss (adaptive thermogenesis) Hormonal changes that defend against weight loss persist Long-Term Management : Most individuals require ongoing medication for sustained weight loss maintenance This is similar to other chronic disease treatments (e.g., blood pressure medications) Obesity is a chronic disease requiring long-term management Strong lifestyle habits help minimize regain but may not prevent it entirely Discuss any plans to discontinue medication with healthcare provider to develop appropriate tapering plan and maintenance strategies
Monitor Body Composition, Not Just the Scale The number on the scale doesnt tell you what youre losing
A comprehensive and updated review on GLP-1 receptor agonists in a clinical perspective
Today, we talk about a JAMA study that outlines the downstream effects of the NIH cutting research costs, see one man survive a likely case of ALS thus far, perhaps thanks to an FUS-targeting drug, and more

Thyroid Medications Because ashwagandha may influence thyroid hormone levels, it may interact with thyroid treatments
Analyst sentiment, while generally leaning towards 'Buy' or 'Moderate Buy' with average price targets suggesting modest upside, also reveals a mixed picture, with some analysts issuing 'Sell' or 'Reduce' ratings due to concerns about slowing outlook and profitability sustainability
