retatrutide more plates more dates New podcast episode out now with @drmikeisraetel Dr Mike Israetel returns to enlighten you on what's coming in the future of health, fitness, and aesthetics. Mike's new book The Aesthetics Revolution is EASL position paper on preclinical

Some is from the medication itself

However, it was never intended to be a mass-market substitute for FDA-approved, patented medications

For the body composition data that informed my tirzepatide choice, see tirzepatide vs semaglutide for athletes

In addition to sustained weight loss, long-term use is associated with continued cardiovascular protection, maintained glycemic control, and progressive improvements in metabolic markers

In the DPP-4/Diprotin A co-crystal structure (PDB ID 1nu8), the peptide bond between the second and third residues is not cleaved after formation of the tetrahedral intermediate, wherein the sidechain of the catalytic serine (Ser630) is covalently linked to the carbonyl carbon atom Pro2

Glucagon directly interacts with vagal afferent nodose ganglion neurons to induce Ca 2+ signaling via glucagon receptors