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Diabetes Care 48 , 846859 (2025)

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Theyve committed to a healthier lifestyle by lowering their weight, and are enjoying the confidence that comes with it, but are now faced with sagging skin, she said

Glucagon-like peptide 1 and its analogs act in the dorsal raphe and modulate central serotonin to reduce appetite and body weight

While there are some similarities between diet-induced and genetic models of obesity, they differ significantly in insulin sensitivity and hormonal profiles, highlighting that obesity-induced effects are not equivalent to those driven by genetic predisposition (35)

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