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For researchers currently building protocols based on Phase 2 data, the Phase 3 dose selection validates the 4mg to 12mg range as the therapeutic window

Semaglutide Nausea or vomiting Diarrhea or constipation Headache or dizziness Fatigue Injection site reactions Rare: pancreatitis or gallbladder issues Mounjaro Nausea or reduced appetite Diarrhea or constipation Stomach pain or indigestion Injection site reactions Headache or dizziness Rare: risk of thyroid tumors (in animal studies) Other potential tirzepatide side effects may include increased heart rate or allergic reactions in rare cases For a deeper breakdown of each symptom and tips on how to manage them, see our full guide on mounjaro side effects

During your first 4-6 weeks on semaglutide injection therapy, temporarily reduce these foods and prioritize easily digestible proteins like chicken, fish, and eggs

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