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Clinical results: The SURMOUNT-1 trial, published in the New England Journal of Medicine, showed tirzepatide produced average weight loss of 20.9 percent at the 15 mg dose
This effect is likely mediated by synergistic interactions between the endogenous cannabinoid system and the endogenous opioid system at both the spinal cord and central nervous system levels [66]
These findings suggest that RETA leads to persistent changes that impair tumor progression even after discontinuing treatment
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