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GLP-1 can cause nausea because it slows down how quickly your stomach empties after you eat

3.1 Clinical trial landscape: observations on effect size and heterogeneity Currently, RCTs of GLP-1RAs in PCOS are generally characterized by small sample sizes, single-center designs, and relatively short follow-up periods

and is "thoroughly vetted by third party scientific and medical experts for claims and safety," the company added

There are alternative medications for addressing obesity and type 2 diabetes

After 52 weeks of semaglutide at up to 2.4 mg once weekly, there was significant weight loss, with an estimated different of 10.7 percentage points compared to placebo ( p 10% weight loss within the first year of intervention was associated with a 21% reduction in cardiovascular mortality [97]

The American Medical Association (AMA) reports that state-level spending on GLP-1s varies, reflecting these differences