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Weight loss from GLP-1 medications does not produce a disproportionate reduction in muscle mass or function in either obese mice or humans

For example, the heart and kidneys have a complex and interconnected relationship

The timeline for results from GLP-1 injections can vary depending on individual factors, but many patients begin noticing a reduction in appetite and modest weight loss within the first few weeks of starting therapy

doi: 10.1111/dom.12548

Kinzig KP, Hargrave SL, Honors MA

Whether the same will extend to humans remains to be seen, but the authors claim their study "provides a strategy for diabetes prevention." The study was published in Nature Microbiology