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Genetic and pharmacogenomic studies implicate GLP1R , ARRB1 (-arrestin-1), and other loci in contributing to interindividual variability (225)
These findings suggest potential hypothalamicpituitaryadrenal axis abnormality due to SARS-CoV-2-induced central adrenal insufficiency
This triggers a cascade of responses including increased insulin release, decreased glucagon secretion, slowed stomach emptying, and reduced appetite
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If these side effects persist or worsen, medical attention should be sought
Merry DE, Korsmeyer SJ
