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All trials were multinational and sponsored by industry (two by Sanofi Aventis, three by Novo Nordisk, one by Eli Lilly, one by AstraZeneca, one by GlaxoSmithKline)

Side Effects: Gastrointestinal side effects, such as nausea, are common initially but can be managed by gradually adjusting the dosage

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In the pathological state of ischemic stroke, inflammatory signals released by dead neurons or cytokines and chemical inducers secreted by microglia under stress could drive circulating lymphocytes to recruit to the damaged brain (61, 62)

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J Gastrointest Surg