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Khan, S

Weight regain is possible if underlying insulin resistance isn't addressed

Maximum dose: 2.4 mg weekly

Always consult with your healthcare provider before starting any new medication or weight loss program

[DOI] [PubMed] [Google Scholar] Xiao Q

Variants in GLP1R (the GLP-1 receptor itself), GIPR (rs1800437 is the headline variant for differential GLP-1 response), FTO (appetite regulation), MC4R (satiety signaling), and TCF7L2 (insulin response) are associated with measurably different response patterns to semaglutide and tirzepatide
