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GLP-1 has a vasodilatory action and anti-atherosclerotic effect [42]
Theres some evidence out there that suggests capsaicin can support reductions in body weight, BMI, and waist circumference, says Richardson

In women, the fibrous cords that connect skin to muscle are arranged in a vertical pattern, making it easier for fat cells to bulge through and create dimples

It is important to note that patients with a history of major depression were actually excluded from the phase 3 randomized controlled trials (RCTs) of these medications 10,11,12,13,14,15,21,22,23

DOI: 10.1056/NEJMoa2416394

[DOI] [PubMed] [Google Scholar] 23.Mechanisms of action and therapeutic application of glucagon-like-1
