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Originally developed as pharmacological agents for the management of Type 2 diabetes mellitus, these molecules which include semaglutide, liraglutide, and tirzepatide have undergone a remarkable scientific reappraisal over the past several years

In China, beyond the in-market products such as semaglutide and tirzepatide and promising global pipeline assets including orforglipron (oral), MariTide (monthly injectable) and retatrutide (triple agonist), a range of China-only molecules is also emerging with strong competitiveness (see Table 2)

Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or treatment and before undertaking a new healthcare regimen

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Additionally, preclinical research suggests GLP-1 receptors may be present in various tissues beyond the pancreas and brain, including synovial tissue and chondrocytes