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Moreover, in a lean mouse model of severe nonalcoholic fatty liver disease, phosphatidylethanolamine N -methyltransferase mice, we observed a 4-fold increase in circulating DPP4, in contrast with previous findings connecting DPP4 release and obesity

GLP-1 receptor agonists do their work by playing a sort of trick on the body, and the body doesnt always like it

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Month 23 Dose Escalation Dose increases on a structured schedule based on tolerability and response

Assuming a 50 percent price erosion post-generic entry and 50 percent market share capture by generics, the addressable opportunity could be around $500 million