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It is also used as monotherapy for adults with relapsed or refractory AML.Cholangiocarcinoma (Bile Duct Cancer): Used for adults with locally advanced or metastatic cholangiocarcinoma who have already received previous systemic treatments.Myelodysplastic Syndromes (MDS): Approved to treat adults with relapsed or refractory MDS.Administration and DosageForm: It comes as a 250 mg oral tablet.Standard Dose: The typical adult dose across approved indications is 500 mg (two tablets) taken orally once daily.Food Restrictions: It can be taken with or without food, but it must not be taken with or immediately after a high-fat meal