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Although the sample size was small with only 48 total participants randomized across the two treatment conditions, the randomized, double-blinded, experimental design provides some compelling preliminary evidence that semaglutide might reduce alcohol craving and the amount of alcohol consumed on drinking days in people with alcohol use disorder not actively seeking treatment

For instance, Emily shared her struggle with the initial side effects of semaglutide, including nausea and reduced appetite, which made it difficult to consume even the limited carbohydrates allowed on the ketogenic diet

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On the flip side, avoid lying down when youre feeling nauseous this can make you feel worse

The TRIUMPH-4 trial studied 445 adults with obesity or overweight and knee osteoarthritis over 68 weeks