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Quality assessment No formal quality scoring tool (e.g., NOS or GRADE) was applied, given the heterogeneity of included study designs

Tirzepatide has been shown to decrease food intake among these other benefits: Significant Weight Loss: Clinical trials have demonstrated that tirzepatide leads to significant weight loss in individuals with obesity and/or type 2 diabetes

This builds a habit and reduces the risk of missing a dose

This ensures the full dose is delivered

When combined with diet and exercise, the average weight loss was 15% and 20%, respectively, compared to 2.4% and 3.1% achieved with diet and exercise alone

Patients with bipolar disorder, severe anxiety, or active eating disorders should discuss the combination carefully with their psychiatrist before starting GLP-1 therapy