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To mark 50 years of monoclonal antibodies, this Review from Chan, Martyn and Carter provides an overview of how antibody engineering strategies have continued to improve antibody-based therapeutics, chiefly focusing on antibody-mediated targeting of B cells and also human epidermal growth factor receptor 2 (HER2)+ cancers
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The studies available as a free text, in the English language and related to humans, were included
It is currently under investigation for obesity, type 2 diabetes, and metabolic dysfunction-associated steatotic liver disease (MASLD)
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