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summary Otherwise known as fibroids Leiomyomas are smooth muscle growths of the uterine myometrium can be intramural submucosal subserosal Often present with multiple discrete tumors Epidemiology benign uterine tumor tumor in females seen in African Americans (5x more common) occurs in women 20-40 years of age Presentation sensitive to estrogen levels tumor growth and increased symptoms during pregnancy decreased symptoms during menopause symptoms depend on location of leiomyoma intramural asymptomatic submucosal intermenstrual bleeding and menorrhagia subserosal compression of bladder, rectum, or ureter pelvic pain urinary or bowel issues uterus is enlarged firm mobile asymmetric nontender multiple tumors IMAGING transvaginal ultrasound has high sensitivity (95-100%) hyperechoic, well-circumscribed round masses STUDIES Labs -hCG to rule out pregnancy Histology whorled pattern of smooth muscle bundles Differential Diagnosis Endometrial polyp Pregnancy Diagnosis Treatment If asymptomatic observation fibroids can shrink substantially postpartum and after menopause If symptomatic NSAIDs for dysmenorrhea OCPs for abnormal uterine bleeding GnRH analogs to shrink fibroids pre-surgery surgical management preserves childbearing potential uterine artery embolization preserves childbearing potential if myomectomy is not an option hysterectomy definitive therapy Complications very rarely (if at all) transforms into leiomyosarcoma infertility Prognosis having symptomatic fibroids decreases quality of life Create a free account or log in to see the cards.

Consult with your nephrologist if you experience the following warning signs: Decrease in urination or a change in urine output Unexplained fatigue or tiredness Persistent vomiting or diarrhea Comparing Ozempic to other options for kidney health Ozempic is very helpful in lowering the progression of kidney disease in patients with or without diabetes

If you are a competitive athlete subject to anti-doping regulations, semaglutide occupies a different space than in standard employment or clinical drug testing