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We included 26 records regarding the safety of GLP-1 agonists during pregnancy and/or lactation ( Supplement 2 , 3 ), and 16 records regarding the safety of SGLT2 inhibitors during pregnancy and/or lactation ( Supplement 2 , 3 )

Heart rate was elevated with RG7697/NNC0090-2746 (5.6 bpm relative to placebo), and 43% of individuals who received the co-agonist developed anti-drug antibodies, although these antibodies did not appear to alter drug efficacy

Consumers should discuss these distinctions with their healthcare provider

Plus, if a doctor prescribes a more effective weight loss medication, it may not be covered by the patients insurance

However, experiences vary from person to person

The FDA-approved GLP-1 medications come in injectable pens with precise dosing, whereas compounded GLP-1 drugs typically come in a vial with a syringe that can offer more flexibility for microdosing, but also opens up the chance for taking too much or too little medication