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Signs that levothyroxine dose adjustment may be needed include symptoms of hyperthyroidism (anxiety, palpitations, tremor, heat intolerance) or worsening hypothyroidism (fatigue, cold intolerance, weight gain despite GLP-1 use)

Guidelines on when to resume semaglutide after surgery and standard pre-surgical fasting recommendations for GLP-1 users should be discussed with your surgical team well in advance of any scheduled procedure

In combination with glimepiride, with or without metformin, sitagliptin provided significant improvements in A1C and FPG compared to placebo (Table 13)

19, 2025 FDA Approves First Generic of Once-Daily GLP-1 Injection to Lower Blood Sugar in Patients with Type 2 Diabetes U.S

Switching compounds or adding a second agent is a clinically sound next step when a single medication reaches its plateau