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While they were in the clinic, a modified Schirmer test confirmed their underproduction of saliva or hyposalivation

doi: 10.1111/nmo.13738 [DOI] [PubMed] [Google Scholar] 26

proper subcutaneous administration ensures optimal absorption, while injection-site reactions may occur if proper rotation is not practiced

Since pharmacokinetic data of the short-acting formulation of Ex applied in the present study is only available for rodents [35] and humans [36] (but not rhesus macaques), the timing of the drug administration and the two sessions was determined based on the behavioural findings of Scott and Moran [22], where the dose-dependent anorectic effects of Ex in rhesus macaque operant food consumption was seen up to 6 h post-administration