retatrutide water retention CONSIDERING “RETA” ? PLEASE READ THIS I'm going to be very direct. If you are being offered “Reta” (retatrutide) for weight loss, do not take it! is: • not registered Retatrutide for weight loss: Study
Description
Tom Miller with University of Utah Hospital

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The most recently approved FDA medication for the treatment of obesity, tirzepatide, exerts its physiologic effects as a dual GLP-1R and Gastric Inhibitory Polypeptide Receptor (GIP-R) agonist with better efficacy than the standalone GIP-R agonist semaglutide [39]

Splitting to twice-weekly reduces peak concentration by approximately 28% while keeping total weekly drug exposure the same, per our pharmacokinetic modeling
Every patient gets a monitored program with regular check-ins, dose adjustments, and lab work as needed

The Wegovy tablet was approved in December, and the uptake has been record-breaking