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Never stop or change dose without medical advice

GLP-1 receptor agonists are a class of medication which have become widely used within the UK under brand names such as Mounjaro weight loss injections and Wegovy injections

According to NICE guidance (NG28), patients on GLP-1 receptor agonists should be reviewed regularly, with continuation based on specific HbA1c reduction and weight loss targets at around 6 months of treatment

260 GLP-1 downregulated Na+/H+ exchanger isoform 3 in the renal proximal tubule of rats, suggesting that GLP-1 could be used to treat hypertension and sodium retention disorders

[97] Patients with pre-existing gastrointestinal conditions may be at increased risk for these side effects and should be monitored accordingly

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