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isocitrate dehydrogenase, -ketoglutarate dehydrogenase, and succinate dehydrogenase, and at the same time reduced generation of reactive oxygen species stabilized the mitochondrial membrane potential, enhanced the levels of ATP, and enhanced the activity of the mitochondrial complex I [94]

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These findings suggest that semaglutide may improve metabolic health by enhancing mitochondrial function in skeletal muscle, independent of its effects on insulin signaling

[DOI] [PubMed] [Google Scholar] 10.Arlt W, Callies F, Allolio B

Jastreboff, et al., 'Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA', Lancet , vol

While cardio has tremendous benefits for our heart and brain health, its not the most effective weight loss approach when taking GLP-1 medications