semaglutide and metformin improve menstrual cyclicity in overweight/obese women with polycystic ovary syndrome: a randomized trial semaglutide vs metformin Efficacy and
Description
(2025, June 17)
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Conclusions Current evidence suggests that GLP-1 receptor agonists might modulate neural systems underlying reward processing by reducing activity within valuation and motivational circuits

Curcumin (turmeric extract): Anti-inflammatory and may enhance GLP-1 levels and insulin sensitivity

JAMA Cardiol (2020) 5(10):118290
the related GLP-1 receptor agonist class improves insulin resistance and some reproductive endpoints in small PCOS trials
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Brenipatide is the one to watch for sobriety and mental health, not for the scale
