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10.1038/nrneurol.2017.185 Nat

Study quality was estimated by Newcastle-Ottawa Quality Assessment Scale (NOS) and Cochrane risk of bias (RoB) version 2 tool, and publication bias was estimated through forest plots and the Eggers test

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Key secondary objectives were to compare the effects of semaglutide 2.4mg to placebo regarding mortality, heart failure, cardiovascular risk factors, including glucose metabolism, body weight and kidney function

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