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doi:10.4103/ijem.ijem_423_21

Gastrointestinal (GIT) adverse events were the most common, leading to the discontinuation of liraglutide

Some people have experienced gastrointestinal issues such as nausea, diarrhea, or constipation, especially early in the treatment
While bupropion works in the brain on dopamine and norepinephrine, tirzepatide works primarily in the gut, the pancreas, and appetite centers in the hypothalamus

Your food diary data from the first two months guides your long-term eating patterns
In November 2023, the FDA expanded this approval to include tirzepatide, branded as Zepbound, for weight loss in individuals without diabetes
