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The treatment, which operates by targeting glucagon-like peptide-1 (GLP-1) receptors, falls within a class of drugs that are designed to affect the bodys insulin production and blood sugar levels

Results show broad benefits with a reduced risk of substance use and psychotic disorders, seizures, neurocognitive disorders (including Alzheimers disease and dementia), coagulation disorders, cardiometabolic disorders, infectious illnesses and several respiratory conditions

Early clinical results suggest the treatment is safe and well tolerated.

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Moreover, our data reveal novel aspects of GLP-1 stimulated insulin secretion involving de novo gene expression.

Retatrutide altered circulating metabolites and lipids linked to fatty acid oxidation and insulin resistance in people with obesity, with or without type 2 diabetes