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In 2005, the first drug, exenatide, derived from Gila monster saliva, hit the market

Tirzepatide is a powerful GLP-1 & GIP receptor agonist that: Stimulates insulin secretion Suppresses glucagon release Delays gastric emptying Reduces appetite and cravings Promotes fat oxidation and weight loss Previously only available via injection , this compound now comes in an easy-to-use microneedle patch that offers slow, stable release over 24 hours pain-free and hassle-free

The GIP component is thought to enhance the metabolic effects of GLP-1 and may also contribute to improved fat metabolism

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the study's lead author and a professor of radiology in the University of Pennsylvania Perelman School of Medicine, said in a statement that the findings were "observational" and do not "definitively confirm an association between GLP-1 medications and reduced breast cancer incidence," however the study "does add to the growing body of evidence suggesting that it's worth investigating these weight-loss drugs as potential cancer prevention tools." Narula reiterated that the new study is "hypothesis-generating" not "practice-changing," though the study does add to a growing body of similar research

On training days, pre-workout fuel is non-negotiable, and so is the window right after